Extended-spectrum ß-lactamases in gram negative bacteria
نویسندگان
چکیده
منابع مشابه
Evolution and spread of SHV extended-spectrum beta-lactamases in gram-negative bacteria.
Resistance to beta-lactam antibiotics has been a problem for as long as these drugs have been used in clinical practice. In clinically significant bacteria the most important mechanism of resistance is the production of one or more beta-lactamases, enzymes that hydrolyse the beta-lactam bond characteristic of this family of antibiotics. Prominent among the beta-lactamases produced by the Entero...
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CTX-M enzymes, the plasmid-mediated cefotaximases, constitute a rapidly growing family of extended-spectrum β-lactamases (ESBLs) with significant clinical impact. CTX-Ms are found in at least 26 bacterial species, particularly in Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis. At least 109 members in CTX-M family are identified and can be divided into seven clusters based on thei...
متن کاملOccurrence of Extended-Spectrum Beta-Lactamases Among Blood Culture Isolates of Gram-Negative Bacteria
Department of Microbiology, Lady Hardinge Medical College and Associated Hospitals, Delhi, India –110001. Received for publication: April 27, 2004. Reprint request: Dr Lata Kapoor, 128, Jailakshmi Apartments, 59, I.P. Extension, Delhi, India PIN110092 E-mail: [email protected]
متن کاملThe Importance of Extended-Spectrum β-lactamases in Gram-Negative Enteric Bacilli and the Phenotypic Methods of detection
The production of β-lactamase enzymes is the main mechanism of resistance to β-lactam antibiotics in gramnegative bacilli. Therefore, it is important to identify the β-lactamases-producing bacteria for the treatment of caused infections. This article aimed to review the recent literature and guidelines regarding phenotypic detection of β-lactamases in common gram-negative bacilli in clinical sa...
متن کاملThe Association Between Genetic Variants in Extended Spectrum Beta-Lactamases and AmpC-producing Gram-Negative Bacilli and Antibiotic Resistance
Background and Objective: A large group of genes associated with extended-spectrum beta-lactamases (ESBL) and AmpC expression is involved in inducing antibiotic resistance in various bacteria. Identifying these genes and assessing their harboring will be crucial in determining the pattern of antibiotic resistance. This study aimed to characterize genetic variants in extended-spectrum beta-lacta...
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ژورنال
عنوان ژورنال: Journal of Global Infectious Diseases
سال: 2010
ISSN: 0974-777X
DOI: 10.4103/0974-777x.68531